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AP Biology: Essential Life Process Information Drill 1, Problem 1. If one parent is heterozygous for the sickle cell trait while the other parent does not carry it, what is the likelihood that their child will be a carrier?

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Transcript

00:03

Here's your shmoop du jour, brought to you by sickle cells.

00:07

If they're that sickle, they really should be at home in bed.

00:13

If one parent is heterozygous for the sickle cell trait while the other parent does not

00:19

carry it, what is the likelihood that their child will be a carrier?

00:24

And here are the potential answers...

00:28

All right, this is a pretty straightforward question... if we know what heterozygous means.

00:32

If we don't... we can always eeny-meeny-miney-moe the answer...

00:39

Let's assign S to represent a normal phenotype and s to represent a sickle cell phenotype:

00:49

In genetics, heterozygous means you have one of the dominant S, and also an abnormal, recessive

00:56

lowercase s.

00:57

This means that one parent has the genotype of big S, big S, and one has the genotype

01:03

big S, small S.

01:05

If we write out a Punnett Square to represent the possible genetic combinations for the child...

01:12

...we'll see that there is a 50% chance of the child being a carrier.

01:19

So...our answer's C!

01:21

Don't worry -- just because both your parents have a big S doesn't mean that you're going to have a... big S.

01:27

No Punnett Square intended.

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